{
  "id": "skill_024b2165ef874c1aa509a07168b27d98",
  "name": "lasso-biomarker-panel",
  "description": "Select minimal biomarker panels using LASSO regularization with nested cross-validation, stability selection, and independent cohort validation.",
  "category": "multi_omics",
  "owner_type": "system",
  "created_by_name": "Phylo",
  "verified": false,
  "icon": "flask",
  "keywords": [],
  "default_message": "Build a LASSO biomarker panel to predict treatment response from gene expression data.",
  "created_at": "2026-04-29T03:43:33.385000",
  "updated_at": "2026-06-02T00:55:59.737000",
  "entrypoint": "SKILL.md",
  "supporting_files": {
    "references/decision-guide.md": {
      "size": 2721,
      "type": "md",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "references/lasso-reference.md": {
      "size": 4133,
      "type": "md",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "references/validation-guide.md": {
      "size": 3873,
      "type": "md",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/biological_interpretation.R": {
      "size": 86941,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/biomarker_plots.R": {
      "size": 13551,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/export_results.R": {
      "size": 63850,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/lasso_workflow.R": {
      "size": 12534,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/load_example_data.R": {
      "size": 101173,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/plotting_helpers.R": {
      "size": 2840,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/prepare_features.R": {
      "size": 8534,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/query_cellxgene.py": {
      "size": 3859,
      "type": "py",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    },
    "scripts/validate_external.R": {
      "size": 6846,
      "type": "R",
      "modified": 1777001735,
      "can_edit": false,
      "editor_kind": null
    }
  },
  "_category_display": "Multi-omics"
}